GlaxoSmithKline (GSK) has issued a consumer advisory warning about a potential health risk associated with long-term, excessive use of GSK's zinc-containing denture adhesives Poligrip Ultra and Poligrip Total Care.
As a precautionary measure GSK has voluntarily stopped the manufacture, distribution and advertising of these products. The move has followed reports of adverse events which, together with published literature, suggested that excessive use of these products, typically for several years, may lead to the development of high levels of zinc in the body, which are associated with neurological symptoms such as numbness, tingling or weakness in the arms and legs, difficulties with walking and balance and blood problems such as anaemia.
The company says that Poligrip Ultra and Poligrip Total Care are safe to use as directed on the product label, which the majority of consumers follow. However, some consumers apply more adhesive than directed and use it more than once per day.
GSK has issued consumer advice in which it instructs consumers who have been using the product correctly that they may continue to do so safely, but must ensure they are using the products as directed on the package.
For those who have been using Poligrip Ultra and Poligrip Total Care for several years in greater amounts than directed on the package, for example using adhesive more than once per day or using up adhesive in a shorter time than directed on the label (a typical 40g tube should last about 6 weeks), or those who have concerns about their health, GSK is advising patients to stop using the product, talk to their doctor and use a zinc-free alternative adhesive.
The company adds that if dentists have any patients who describe neurological symptoms associated with long-term excessive denture adhesive use, they should refer the patient to their GP for assessment and ask that dentists report the case to GSK at 0208 047 2500. Any other consumer queries can be directed to its consumer call line at 0800 988 6366. The return of Poligrip samples should be arranged via your GSK representative.
