dental hygienist and patient in full PPE gear having a conversation






Don’t let patients with
sensitivity settle for less

Colgate Total Sf toothpaste tube with the color circle on it


How does the Pro-Argin technology work?


The effectiveness of Colgate® SENSITIVE INSTANT Relief toothpaste is built on its Pro-Argin technology with arginine and calcium from calcium carbonate. It effectively occludes open dentine tubuli instantly* and builds a strong calcium-rich layer that ensures long-lasting relief from the pain of sensitivity.1,2 The protective layer remains strong even after exposure to acid attacks.3

Watch the video to learn more

Superior dentine tubule occlusion vs

competitive technologies4,5


In vitro study shows the effective dentine tubule occlusion of

Colgate® SENSITIVE INSTANT Relief with Pro-Argin technology3,#

Colgate Sensitive Instant Relief - Stannous Fluoride Comparison

One clinically proven solution for instant*

and long-lasting relief1,2


What patients say about 



Register now and gain access to:

  • 8 hours ECPD
  • Product samples
  • Patient materials


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* For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute.

‡ Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride.

† Lasting relief with 2x daily continued brushing.

# In-vitro study, actual confocal images after 5 treatments.

1 Nathoo et al. J Clin Dent. 2009;20 (Spec Iss):123–130. 2 Docimo et al. J Clin Dent. 2009; 20 (Spec Iss): 17–22. 3 Report Deon Hines-0003, 2016. 4 Hines D et al. Poster #3406, July 2018 IADR. Colgate-Palmolive Company 2018. 5 Hines D et al. Poster #0742, March 2018 AADR. Colgate-Palmolive Company 2018. 6 Ipsos, Romania Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2-week trial, 545 respondents, 2015. 7 Ipsos, UK Patient Experience Programme on Colgate® SENSITIVE PRO-Relief, results collected after 2 weeks trial, 192 respondents, 2016.