Proactive prevention has never been more important - Empower every patient to achieve superior biofilm control¹ ² *

Colgate Total^®with Dual-Zinc + Arginine enables superior biofilm control.^*,1,2 An in-vitro study showed that Colgate Total^® is highly effective in controlling bacteria across the whole mouth and in saliva. Clinical findings revealed reductions up to 41% higher than those obtained through brushing with a regular fluoride toothpaste alone.⁴ 

Furthermore, superior# clinical outcomes were confirmed in numerous clinical studies,^5-7 demonstrating significantly better control of plaque, gum problems,tartar and malodour, compared to a standard non-antibacterial sodium fluoride toothpaste. 

● Plaque reduction - 34.4%^{5,^} 

● Malodour reduction - 30.8%^{7,^}

● Reduction in gum problems - 26.6%^{5,^} 

● Reduction in tartar - 40.1%^{6,^}

Colgate Total^® is the advanced way to achieve Whole Mouth Health by proactively controlling and protecting against bacteria on 100% of mouth surfaces, Teeth, Tongue, Cheeks and Gums.^†† 

Empower every one of your patients by recommending Colgate Total^® so that they can achieve superior biofilm control^1,2,††​ for better, more complete oral health. 

Click here for further information on how you can achieve effective biofilm management with Colgate Total^®. 

ENDS 

* Colgate Total^® provides superior in-vitro delivery, penetration, and retention of Zinc through Arginine technology for biomass reductions vs Zinc control toothpaste. 

† Mass spectrometry images of salivary 10-day biofilms treated once with toothpaste slurry and regrown overnight under constant artificial salivary flow (10 mL/hr). 

‡ Confocal images of established salivary 40-hour biofilms grown in-vitro under flow and then treated once for 2 minutes with water control (top) or Dual-Zinc + Arginine technology (bottom). 

§ Bacterial biofilms imaged after one treatment with either non-antibacterial fluoride toothpaste or Dual Zinc + Arginine toothpaste slurry followed by a 12-hour regrowth period. 

# Compared with non-bacterial sodium fluoride toothpaste. 

^ Statistically significant reduction vs non-antibacterial fluoride toothpaste. 

†† vs ordinary non-anti-bacterial fluoride toothpaste. 

1. Manus L, et al. J Clin Dent 2018;29(Spec Iss A)A10–19. 2. Daep C, et al. August 2019, data on file. 3. Sanz et al, J Clin Periodontol. 2017;44(Suppl 18):S5–S11. 4. Prasad K et al, J 

Clin Dent 2018;29 (Spec Iss A). 5. Li X, et al. J Dent Res 2019;98 (Sepc Iss A):3444. 6. Seriwatanachai & Mateo, Sept 2016, data on file. 7. Hu D, et al. J Clin Dent 2018;29 (Spec Iss A) A41-45.