Colgate® MAXIMUM Cavity protection KIDS Plus Sugar Acid Neutraliser™

Overview

Colgate® Maximum Cavity Protection KIDS PLUS Sugar Acid Neutraliser™ is the only Children’s toothpaste powered by 1450ppm fluoride plus Arginine and insoluble Calcium compounds provides a new standard of care in everyday cavity protection for children and young families.

PRODUCT CHARACTERISTICS

Everyday protection for children and young families
Mild mint flavour to aid child compliance
Helps fight cavities before they form1,2
Directly targets and neutralises sugar acids in plaque
Restores pH to a healthier level
Provides greater cavity protection versus a regular fluoride toothpaste3
Fluoride helps by promoting remineralisation and decreasing demineralisation
Sugar Acid Neutraliser™ Technology creates a healthy environment that allows fluoride to effectively help remineralise the tooth enamel
Available in a family toothpaste variant

PRODUCT BENEFITS

Reduces demineralisation*3
4X greater remineralisation*3
Up to 20% fewer new cavities in 2 years§4,5
Suitable for all children 3 years and over

* Results from a remineralisation study vs a regular fluoride toothpaste, both with 1450 ppm fluoride.

§ Results from two 2-year clinical study vs a regular fluoride toothpaste, both with 1450 ppm fluoride.

References:

1. Wolff M, Corby P, Klaczany G, et al. J Clin Dent. 2013;24(Spec Iss A):A45-A54. 2. Santarpia P, Lavender S, Gittins E, et al. Am J Dent. 2014;27(2):100-5. 3. Cantore R, Petrou I, Lavender S, et al. J Clin Dent. 2013;24(Spec Iss A):A32-A44. 4. Kraivaphan P et al. Caries Res 2013;47:582-590. 5. Hu DY et al. 2013 Data on file. Colgate-Palmolive Company. 6. Hu DY, Yix W, Li X, et al. J Clin Dent. 2013:24 (Spec Iss A):A23-A31. 7. Souza MLR, Cury JA, Tenuta LMA, et al. J Dent. 2013;doi:10.1016/j.jdent.2010.04.006. 8. Srisilapanan P, Korwanich N, Yin W, et al. J Dent. 2013;doi:10.1016/j.jdent2010.04.005.

Clinical Research

Two-Year Caries Clinical Study Conducted in China of the Efficacy of Novel Dentifrices Containing 1.5% Arginine, an Insoluble Calcium Compound and 1450 ppm Fluoride
DY Hu1, X Li1, W Yin1, XJ Jiang1, XM Zhang1, LR Mateo2, W DeVizio3, YP Zhang3
The Anti-caries Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride as Sodium Monofluorophosphate Assessed Using Quantitative Light-induced Fluorescence (QLF)
W Yin1, DY Hu1, X Li1, X Fan1, YP Zhang2, IA Pretty3, LR Mateo4, D Cummins2, RP Ellwood3
Comparing the Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride to a Dentifrice Containing 1450 ppm Fluoride Alone in the Management of Primary Root Caries
MLR Souza, JA Cury, LM Tenuta, YP Zhang, LR Mateo, D Cummins, RP Ellwood
A Clinical Investigation of the Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride as Sodium Monofluorophosphate in a Calcium Base, on Primary Root Caries
DY Hu1, W Yin1, X Li1, Y Feng2, YP Zhang3, D Cummins3, LR Mateo4, RP Ellwood5
Comparison of the Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride to a Dentifrice Containing 1450 ppm Fluoride Alone in the Management of Early Coronal Caries as Assessed Using Quantitative Light-induced Fluorescence
P Srisilapanan1, N Korwanich1, W Yin2, C Chuensuwonkul3, LR Mateo4, YP Zhang5, D Cummins5, RP Ellwood6
in-situ-clinical-effects-of-new-dentifrices-containing-1-5-arginine-and-fluoride-on-enamel-de-and-re-mineralization-and-plaque-metabolism
R Cantore1, I Petrou1, S Lavender1, P Santarpia1, Z Liu1, E Gittens1, M Vandeven1, D Cummins1, R Sullivan1, N Utgikar2
In Vivo Effects of a New Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride on Plaque Metabolism
M Wolff1, P Corby1, G Klaczany1, P Santarpia2, S Lavender2, E Gittens2, M Vandeven2, D Cummins2, R Sullivan2
The development and validation of a new technology, based upon 1.5% arginine, an insoluble calcium compound and fluoride, for everyday use in the prevention and treatment of dental caries
D. Cummins*
The caries continuum: Opportunities to detect, treat and monitor the re-mineralization of early caries lesions
I.A. Pretty *, R.P. Ellwood
The Anti-caries Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride as Sodium Monofluorophosphate Assessed Using Quantitative Light-induced Fluorescence (QLF)
W Yin1, DY Hu1, X Li1, X Fan1, YP Zhang2, IA Pretty3, LR Mateo4, D Cummins2, RP Ellwood3
Comparison of the Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride to a Dentifrice Containing 1450 ppm Fluoride Alone in the Management of Early Coronal Caries as Assessed Using Quantitative Light-induced Fluorescence
P Srisilapanan1, N Korwanich1, W Yin2, C Chuensuwonkul3, LR Mateo4, YP Zhang5, D Cummins5, RP Ellwood6
Comparing the Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride to a Dentifrice Containing 1450 ppm Fluoride Alone in the Management of Primary Root Caries
MLR Souza, JA Cury, LM Tenuta, YP Zhang, LR Mateo, D Cummins, RP Ellwood
Establishing a new standard in cavity protection: Introducing Pro-Argin plus fluoride-a breakthrough technology
D. Cummins
Dental Caries: A Disease Which Remains a Public Health Concern in the 21st Century The Exploration of a Breakthrough Technology for Caries Prevention
D. Cummins
A Clinical Investigation Using Quantitative Light-Induced Fluorescence (QLF) of the Anticaries Efficacy of a Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride as Sodium Monofluorophosphate
W. Yin D.Y. Hu X. Fan, , Y. Feng,Y.P. Zhang D. Cummins, L.R. Mateo, I.A. Pretty R.P. Ellwood
In Situ Clinical Effects of New Dentifrices Containing 1.5% Arginine and Fluoride on Enamel De- and Remineralization and Plaque Metabolism
R. Cantore I. Petrou S. Lavender P. Santarpia Z. Liu E. Gittins M. Vandeven D. Cummins R. Sullivan, N. Utgikar
In Vivo Effects of a New Dentifrice Containing 1.5% Arginine and 1450 ppm Fluoride on Plaque Metabolism
M Wolff1, P Corby1, G Klaczany1, P Santarpia2, S Lavender2, E Gittens2, M Vandeven2, D Cummins2, R Sullivan2
Dental Caries: A Disease Which Remains a Public Health Concern in the 21st Century The Exploration of a Breakthrough Technology for Caries Prevention
D. Cummins

Information

PRODUCT INFORMATION

Product Indication:

For everyday cavity protection for children aged 3 years and over

Product Benefits:

Fights sugar acids in plaque–the # 1 cause of cavities1,2

Reduces demineralization*3

4X greater remineralisation*3

Up to 20% fewer new cavities in 2 years§4,5

Mode of Action:

Sugar Acid Neutraliser™ Technology neutralises sugar acids in plaque, restoring pH at the tooth’s surface to a healthy level. This works in combination with 1450ppm fluoride that helps inhibit demineralization and promotes remineralisation. Active Ingredient(s) and Content of Fluoride: 1.5% arginine and 1450ppm fluoride as sodium monofluorophosphate

Contains:

1.5% arginine and 1450 ppm fluoride as sodium monofluorophosphate

*Results from a remineralisation study vs a regular fluoride toothpaste, both with 1450 ppm fluoride.

§Results from two 2-year clinical study vs a regular fluoride toothpaste, both with 1450 ppm fluoride.

References:

1. Wolff M, Corby P, Klaczany G, et al. J Clin Dent. 2013;24(Spec Iss A):A45-A54. 2. Santarpia P, Lavender S, Gittins E, et al. Am J Dent. 2014;27(2):100-5. 3. Cantore R, Petrou I, Lavender S, et al. J Clin Dent. 2013;24(Spec Iss A):A32-A44. 4. Kraivaphan P et al. Caries Res 2013;47:582-590. 5. Hu DY et al. 2013 Data on file. Colgate-Palmolive Company.

FAQs

WHAT IS COLGATE^® MAXIMUM CAVITY PROTECTION KIDS PLUS SUGAR ACID NEUTRALISER™ TOOTHPASTE?

Colgate^® Maximum Cavity Protection KIDS PLUS Sugar Acid Neutraliser™ toothpaste is an everyday anti-cavity toothpaste for children aged 3 years and over, containing Sugar Acid Neutraliser™ Technology and 1450 ppm fluoride

WHAT IS THE FLAVOUR OF COLGATE^® MAXIMUM CAVITY PROTECTION KIDS PLUS SUGAR ACID NEUTRALISER™ TOOTHPASTE?

Colgate^® Maximum Cavity Protection KIDS PLUS Sugar Acid Neutraliser™ toothpaste has a mild mint flavour

WHAT IS SUGAR ACID NEUTRALISER™ TECHNOLOGY?

Sugar Acid Neutraliser™ is Colgate’s trademark name for the technology that has been developed to deliver maximum cavity protection consisting of arginine and an insoluble calcium compound. In Colgate^® Maximum Cavity Protection KIDS PLUS Sugar Acid Neutraliser™ toothpaste, the insoluble calcium compound is calcium carbonate

WHAT IS THE LEVEL OF ARGININE IN COLGATE^® MAXIMUM CAVITY PROTECTION KIDS PLUS SUGAR ACID NEUTRALISER™ TOOTHPASTE?

Colgate^® Maximum Cavity Protection KIDS PLUS Sugar Acid Neutraliser™ toothpaste contains 1.5% Arginine. 1.5% Arginine has been shown as the optimum level for everyday cavity protection, proven to result in up to 20% fewer new cavities in 2 years^§1,2

HOW DOES COLGATE^® CAVITY PROTECTION KIDS PLUS SUGAR ACID NEUTRALISER™ TOOTHPASTE WORK?

The breakdown of dietary sugars by some plaque bacteria produces acids. Colgate’s unique Sugar Acid Neutraliser™ technology is powered by arginine, a naturally occurring amino acid. The Arginine is metabolised by other plaque bacteria to produce base. This helps to neutralise the acids produced by the breakdown of dietary free sugars, helping to restore pH in the plaque biofilm to a neutral and healthier level

WHAT IS THE FLUORIDE CONTENT OF COLGATE^® MAXIMUM CAVITY PROTECTION KIDS PLUS SUGAR ACID NEUTRALISER™ TOOTHPASTE?

Colgate^® Maximum Cavity Protection KIDS PLUS Sugar Acid Neutraliser™ toothpaste contains 1450ppm fluoride as sodium monofluorophosphate to protect against cavities

WHAT AGE IS COLGATE^® MAXIMUM CAVITY PROTECTION KIDS PLUS SUGAR ACID NEUTRALISER™ TOOTHPASTE SUITABLE FROM?

Colgate^® Maximum Cavity Protection KIDS PLUS Sugar Acid Neutraliser™ toothpaste is for children aged 3+. It contains 1450ppm fluoride and has a mild mint flavour to make it more acceptable to younger children.

HOW LONG CAN A PATIENT USE COLGATE^® MAXIMUM CAVITY PROTECTION KIDS PLUS SUGAR ACID NEUTRALISER™ TOOTHPASTE?

Colgate^® Maximum Cavity Protection PLUS Sugar Acid Neutraliser™ toothpaste is an everyday toothpaste for cavity protection. There is no contraindication against prolonged use

§ Results from two 2-year clinical study vs a regular fluoride toothpaste, both with 1450 ppm fluoride.

References:

1. Kraivaphan P et al. Caries Res 2013;47:582-590. 2. Hu DY et al. 2013 Data on file. Colgate-Palmolive Company.

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Colgate® MAXIMUM Cavity protection KIDS Plus Sugar Acid Neutraliser™

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Overview

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Information

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