The next generation of biofilm control:
Colgate Total with Dual-Zinc + Arginine

Discover the problem of uncontrolled biofilm

Uncontrolled biofilms are the primary cause of common oral conditions. Colgate Total, with its  next generation technology controls biofilm by fighting bacteria on the teeth, tongue, cheeks, and gums for whole mouth health.
 

See how Colgate Total with Dual-Zinc + Arginine works

Effective biofilm control is difficult to achieve with ordinary non-antibacterial fluoride toothpastes. New Colgate Total is different. Formulated with Dual-Zinc plus Arginine, it optimizes delivery, penetration, and retention of zinc to inhibit bacterial regrowth.

Discover how superior biofilm control
can be achieved in 3 steps

* In vitro study.
‡Colgate Total® provides superior in vitro delivery, penetration, and retention of Zinc through Arginine technology for biomass reductions vs Zinc control toothpaste
† Mass spectrometry images of salivary 10-day biofilms treated once with toothpaste slurry and regrown overnight under constant artificial salivary flow (10 mL/hr).
‡ Confocal images of established salivary 40-hour biofilms grown in vitro under flow and then treated once for 2 minutes with water control (top) or Dual-Zinc + Arginine technology (bottom).
§ Bacterial biofilms imaged after one treatment with either non-antibacterial fluoride toothpaste or Dual Zinc + Arginine toothpaste slurry followed by a 12-hour regrowth period.

1 Manus L, et al. J Clin Dent 2018;29(Spec Iss A)A10-19.
2 Daep C, et al. August 2019, data on file.

Up to 41% reduction of
bacteria on teeth, tongue,
cheeks and gums*3

Up to 41% reduction of bacteria on teeth, tongue, cheeks and gums

* Statistically significant greater reduction of cultivable bacteria on teeth, tongue, cheeks, and gums with Colgate Total® vs non-antibacterial fluoride toothpaste at 4 weeks, 12 hours after brushing.

3 Prasad K, et al. J Clin Dent 2018;29(Spec lss A):A25-325. here

Click on each benefit and tell your patients how Colgate Total® delivers comprehensive benefits for the whole mouth*
Click on each benefit and tell your patients how Colgate Total® delivers comprehensive benefits for the whole mouth*
Total Wheel
* Clinical and laboratory data on file. See specific benefit area for exact reference.

Reduces Plaque

Colgate Total® helped patients achieve superior reductions in plaque vs ordinary non-antibacterial fluoride toothpaste*¹ 
Plaque Index 
Plaque Index
Plaque Index

*Statistically significant reduction vs non-antibacterial fluoride toothpaste (p˂0.001).
Reference: 1. Delgado E et al, J Clin Dent 2018;29 (Spec Iss A)

Helps Prevent Gum Problems

Colgate Total® helped patients achieve superior reductions in gum problems vs ordinary non-antibacterial fluoride toothpaste*¹
Gingival Index 
Gingival Index
Gingival Index

*Statistically significant reduction vs non-antibacterial fluoride toothpaste (p˂0.001).
Reference: 1.Delgado E et al, J Clin Dent 2018;29 (Spec Iss A)

Prevents Tartar

Colgate Total® helped patients achieve superior reductions in tartar vs ordinary non-antibacterial fluoride toothpaste*¹
Tartar Index 
Tartar Index
Tartar Index

*Statistically significant reduction vs non-antibacterial fluoride toothpaste (p˂0.001).
Reference: 1. Data on file, Seriwatanachai D et al, Colgate Palmolive Technology Center, Piscataway, Sep 2016

Anti-sensitivity

Colgate Total® helped patients achieve superior reductions in sensitivity vs ordinary non-antibacterial fluoride toothpaste*¹

Percent reduction in sensitivity to stimuli
vs ordinary fluoride toothpaste

Superior reduction in Sensitivity

*After 8 weeks.
Reference: 1. Data on file, Seriwatanachai D et al, Colgate Palmolive Technology Center, Piscataway, USA, January 2016

Removes stains

Colgate Total® is clinically proven to reduce stains and stain intensity*¹

Percent reduction vs non-whitening toothpaste*
6 week stain removal clinical study

Removes stains

*Colgate Total® Whitening 1450ppm fluoride toothpaste
Reference: 1. Data on File, Delgado E et al, Colgate Palmolive Technology Center, Piscataway, February 2017

Freshens Breath

Colgate Total® is clinically proven to keep breath fresher over 12 hours*¹
Freshens Breath
Freshens Breath

*Statistically significant reduction vs. non-antibacterial ordinary fluoride toothpaste 12 hours overnight with continuous use for 3 weeks.
Reference: 1. Hu D et al, J Clin Dent 2018;29 (Spec Iss A)

Fight Cavities

Colgate Total® contains sodium fluoride, which has been clinically proven to help prevent tooth decay and cavities by:

  • Inhibiting demineralisation and promoting remineralisation.
  • Making teeth less susceptible to acids that cause decay.
  • New Colgate Total® contains 1450ppmF- is aligned with DBOH guidance1

Reference: 1. Recommended fluoride level (1350-1500ppm) for caries prevention in ‘Delivering better oral health. An evidence-based toolkit for prevention’. 3rd edition, Public Health England, June 2014.

Fight Cavities

Protects Enamel

Colgate Total® helps repair weakened enamel
Laboratory study
Protects enamel
  • Plaque

    Colgate Total® helped patients achieve superior reductions in plaque vs ordinary non-antibacterial fluoride toothpaste*¹

    Plaque Index 

    Plaque Index
    Plaque Index

    *Statistically significant reductions vs non-antibacterial fluoride tootpaste (p<0.001).
    Reference: 1. Garcia-Godoy F, et al. J Clin Dent, submitted August 2018.

  • Gum Problems

    Colgate Total® helped patients achieve superior reductions in gum problems vs ordinary non-antibacterial fluoride toothpaste*¹

    Gingival Index 

    Gingival Index
    Gingival Index

    *Statistically significant reductions vs non-antibacterial fluoride tootpaste (p<0.001).
    Reference: 1. Garcia-Godoy F, et al. J Clin Dent, submitted August 2018.

  • Tartar

    Colgate Total® helped patients achieve superior reductions in tartar vs ordinary non-antibacterial fluoride toothpaste*¹

    Tartar Index 

    Tartar Index
    Tartar Index

    *Statistically significant reductions vs non-antibacterial fluoride tootpaste (p<0.001).
    Reference: 1. Sertwatanachal & Mateo, September 2016, Internal report.

  • Sensitivity

    Colgate Total® helped patients achieve
    superior reductions in sensitivity vs ordinary
     non-antibacterial fluoride toothpaste*¹
    Percent reduction in sensitivity to stimuli
    vs ordinary fluoride toothpaste
    Sensitivity

    *After 8 weeks.
    Reference: 1. Sertwatanachal & Mateo, January 2016, Internal report.

  • Whitening Stain Removal

    Colgate Total® is clinically proven to 
    reduce stains and stain intensity*¹
    Percent reduction vs non-whitening toothpaste*
    6 week stain removal clinical study

    Removes stains

    *Colgate Total® Pro Gum Health Whitening 1450ppm fluoride toothpaste.
    Reference: 1. Garcia-Godoy & Mateo, Febuary 2017, Internal report.

  • Fresh Breath

    Colgate Total® is clinically proven to 
     
    keep breath fresher over 12 hours*¹
    Freshens Breath
    Freshens Breath

    *Statistically significant reductions vs non-antibacterial fluoride tootpaste 12 hours overnight with continuous use for 3 weeks.
    Reference: 1.  Hu D, et al. J Clin Dent, submitted August 2018.

  • Cavity

    Colgate Total® contains sodium
    fluoride, which has been clinically proven to
     
    help prevent tooth decay and cavities by:
    Cavities protection
  • Enamel Protection

    Colgate Total® helps repair 
    weakened enamel
    Enamel protection

The rationale behind whole mouth health for everyday prevention

White paper

The evolving understanding of mouth biology, modern patient demands and advances in oral care technology drive the need to consider ‘the next generation of prevention’ to achieve and maintain oral health. Colgate® believes this need is best met by a Whole Mouth Health approach that elevates the importance of oral prevention and of achieving better oral health outcomes for all patients.

Read the White Paper on Whole Mouth Health - The Next Generation of every day prevention in Oral Health.
 

Whole Mouth Health

Perio and Caries Project

The 'Perio & Caries’ Project of EFP (The European Federation of Periodontology) builds on the outcomes of the expert workshop devoted to “The boundaries between dental caries and periodontal disease”, jointly organised by the EFP with ORCA (European Organisation for Caries Research).

The consensus reports supported by robust systematic reviews  provide a comprehensive scientific framework for how to understand and approach the simultaneous management of caries and periodontal diseases, including specific recommendations for every day prevention.

Perio and Caries Project Intro

Empower every patient to achieve superior biofilm control for Whole Mouth Health#4

Colgate® Total

# Statistically significant greater reduction of cultivable bacteria on teeth, tongue, cheeks, and gums with Colgate Total® vs non-antibacterial fluoride toothpaste at 4 weeks, 12 hours after brushing.

4. Prasad K, et al. J Clin Dent 2018;29(Spec lss A):A25-325.