
Scroll down to see what's possible with Colgate Total®
Discover the problem of uncontrolled biofilm
Uncontrolled biofilms are the primary cause of common oral conditions. Colgate Total, with its next generation technology controls biofilm by fighting bacteria on the teeth, tongue, cheeks, and gums for whole mouth health.
See how Colgate Total with Dual-Zinc + Arginine works
Effective biofilm control is difficult to achieve with ordinary non-antibacterial fluoride toothpastes. New Colgate Total is different. Formulated with Dual-Zinc plus Arginine, it optimizes delivery, penetration, and retention of zinc to inhibit bacterial regrowth.
* In vitro study.
‡Colgate Total® provides superior in vitro delivery, penetration, and retention of Zinc through Arginine technology for biomass reductions vs Zinc control toothpaste
† Mass spectrometry images of salivary 10-day biofilms treated once with toothpaste slurry and regrown overnight under constant artificial salivary flow (10 mL/hr).
‡ Confocal images of established salivary 40-hour biofilms grown in vitro under flow and then treated once for 2 minutes with water control (top) or Dual-Zinc + Arginine technology (bottom).
§ Bacterial biofilms imaged after one treatment with either non-antibacterial fluoride toothpaste or Dual Zinc + Arginine toothpaste slurry followed by a 12-hour regrowth period.
1 Manus L, et al. J Clin Dent 2018;29(Spec Iss A)A10-19.
2 Daep C, et al. August 2019, data on file.

* Statistically significant greater reduction of cultivable bacteria on teeth, tongue, cheeks, and gums with Colgate Total® vs non-antibacterial fluoride toothpaste at 4 weeks, 12 hours after brushing.
3 Prasad K, et al. J Clin Dent 2018;29(Spec lss A):A25-325. here
Reduces Plaque
Colgate Total® helped patients achieve superior reductions in plaque vs ordinary non-antibacterial fluoride toothpaste*¹
Plaque Index


*Statistically significant reduction vs non-antibacterial fluoride toothpaste (p˂0.001).
Reference: 1. Delgado E et al, J Clin Dent 2018;29 (Spec Iss A)
Helps Prevent Gum Problems
Colgate Total® helped patients achieve superior reductions in gum problems vs ordinary non-antibacterial fluoride toothpaste*¹
Gingival Index


*Statistically significant reduction vs non-antibacterial fluoride toothpaste (p˂0.001).
Reference: 1.Delgado E et al, J Clin Dent 2018;29 (Spec Iss A)
Prevents Tartar
Colgate Total® helped patients achieve superior reductions in tartar vs ordinary non-antibacterial fluoride toothpaste*¹
Tartar Index


*Statistically significant reduction vs non-antibacterial fluoride toothpaste (p˂0.001).
Reference: 1. Data on file, Seriwatanachai D et al, Colgate Palmolive Technology Center, Piscataway, Sep 2016
Anti-sensitivity
Colgate Total® helped patients achieve superior reductions in sensitivity vs ordinary non-antibacterial fluoride toothpaste*¹
Percent reduction in sensitivity to stimuli
vs ordinary fluoride toothpaste

*After 8 weeks.
Reference: 1. Data on file, Seriwatanachai D et al, Colgate Palmolive Technology Center, Piscataway, USA, January 2016
Removes stains
Colgate Total® is clinically proven to reduce stains and stain intensity*¹
Percent reduction vs non-whitening toothpaste*
6 week stain removal clinical study

*Colgate Total® Whitening 1450ppm fluoride toothpaste
Reference: 1. Data on File, Delgado E et al, Colgate Palmolive Technology Center, Piscataway, February 2017
Freshens Breath
Colgate Total® is clinically proven to keep breath fresher over 12 hours*¹


*Statistically significant reduction vs. non-antibacterial ordinary fluoride toothpaste 12 hours overnight with continuous use for 3 weeks.
Reference: 1. Hu D et al, J Clin Dent 2018;29 (Spec Iss A)
Fight Cavities
Colgate Total® contains sodium fluoride, which has been clinically proven to help prevent tooth decay and cavities by:
- Inhibiting demineralisation and promoting remineralisation.
- Making teeth less susceptible to acids that cause decay.
- New Colgate Total® contains 1450ppmF- is aligned with DBOH guidance1
Reference: 1. Recommended fluoride level (1350-1500ppm) for caries prevention in ‘Delivering better oral health. An evidence-based toolkit for prevention’. 3rd edition, Public Health England, June 2014.

Protects Enamel
Colgate Total® helps repair weakened enamel


The evolving understanding of mouth biology, modern patient demands and advances in oral care technology drive the need to consider ‘the next generation of prevention’ to achieve and maintain oral health. Colgate® believes this need is best met by a Whole Mouth Health approach that elevates the importance of oral prevention and of achieving better oral health outcomes for all patients.
Read the White Paper on Whole Mouth Health - The Next Generation of every day prevention in Oral Health.

The 'Perio & Caries’ Project of EFP (The European Federation of Periodontology) builds on the outcomes of the expert workshop devoted to “The boundaries between dental caries and periodontal disease”, jointly organised by the EFP with ORCA (European Organisation for Caries Research).
The consensus reports supported by robust systematic reviews provide a comprehensive scientific framework for how to understand and approach the simultaneous management of caries and periodontal diseases, including specific recommendations for every day prevention.

Empower every patient to achieve superior biofilm control for Whole Mouth Health#4

# Statistically significant greater reduction of cultivable bacteria on teeth, tongue, cheeks, and gums with Colgate Total® vs non-antibacterial fluoride toothpaste at 4 weeks, 12 hours after brushing.
4. Prasad K, et al. J Clin Dent 2018;29(Spec lss A):A25-325.